Mikael Pittet
PhD
Professor of Pathology
👥Biography 个人简介
Mikael Pittet has applied single-cell genomics to map CAF heterogeneity and functional subtypes in cancer, revealing distinct populations with opposing functions. His work characterized myofibroblastic CAFs (myCAFs) and inflammatory CAFs (iCAFs) as functionally distinct subtypes with different roles in tumor architecture and immune modulation. He demonstrated that CAF subtype composition correlates with immunotherapy response and patient prognosis. His spatial and single-cell profiling approaches have transformed understanding of stromal complexity in solid tumors.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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