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Translational Medicine / 转化医学DIPG H3K27M Pediatric, Neurological Tumor Biology

Michelle Monje

MD PhD

🏢Stanford University🌐USA

Professor

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Key Contributions

👥Biography 个人简介

Michelle Monje at Stanford has been a leading researcher in DIPG (diffuse intrinsic pontine glioma) — one of the most lethal pediatric brain tumors, typically driven by H3K27M histone mutations. Her work on H3K27M biology, tumor-neuronal interactions in cancer neuroscience, and translational research contributing to ONC201 (dopamine receptor D2 antagonist with ONC201 activity in H3K27M glioma) has been important for this devastating pediatric cancer with historically no effective therapy.

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🧪Research Fields 研究领域

DIPG diffuse intrinsic pontine glioma H3K27M
H3K27 histone mutation glioma
ONC201 DIPG H3K27M
pediatric high-grade glioma biology
cancer neuroscience tumor microenvironment

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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