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Translational Medicine / 转化医学HER2+ Gastric Cancer, Advanced GEJ

Michelle Bhatt

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Associate Professor of Gastrointestinal Oncology

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👥Biography 个人简介

Michelle Bhatt is an expert in HER2-positive gastric and gastroesophageal junction cancer, an area where HER2 targeting was established following the ToGA trial. Her research has characterized the high degree of HER2 intratumoral heterogeneity in gastric cancer compared to breast cancer and its implications for trastuzumab efficacy. She has contributed to development of T-DXd in HER2-positive gastric cancer and studied mechanisms of trastuzumab resistance in this tumor type. Her work advances precision treatment of upper GI malignancies.

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🧪Research Fields 研究领域

HER2+ gastric cancer trastuzumab
ToGA trial
T-DXd gastric DESTINY-Gastric
PD-L1 HER2 combination
gastric HER2 heterogeneity

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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