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Translational Medicine / 转化医学Mantle Cell Lymphoma, BTK Inhibitors, Brexucabtagene

Michael Wang

MD

🏢MD Anderson Cancer Center🌐USA

Professor

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Key Papers
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Key Contributions

👥Biography 个人简介

Michael Wang at MD Anderson has been a leading researcher in mantle cell lymphoma (MCL), contributing to the development of ibrutinib, venetoclax, and subsequently brexucabtagene autoleucel (ZUMA-2 trial) for relapsed/refractory MCL. His work on non-covalent (reversible) BTK inhibitors (pirtobrutinib) for BTK inhibitor-resistant MCL addresses the critical challenge of resistance after covalent BTK inhibitor therapy in this typically incurable lymphoma.

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🧪Research Fields 研究领域

mantle cell lymphoma ibrutinib BTK
brexucabtagene autoleucel MCL CAR-T
MCL ZUMA-2 CAR-T
pirtobrutinib non-covalent BTK MCL
mantle cell lymphoma genomics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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