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Translational Medicine / 转化医学Advanced Prostate Cancer, Resistance Mechanisms

Michael Morris

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Medical Oncologist

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Key Contributions

👥Biography 个人简介

Michael Morris is a leading expert in advanced prostate cancer treatment and biomarker development. His research characterized AR-V7 splice variant expression as a predictor of resistance to enzalutamide and abiraterone, fundamentally altering treatment sequencing. He has led trials of PARP inhibitors in HRR-deficient prostate cancer and studied how PTEN loss affects treatment selection. His work on composite clinical trial endpoints has influenced regulatory approaches to prostate cancer drug approval.

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🧪Research Fields 研究领域

CRPC AR resistance
cabazitaxel prostate
olaparib prostate HRR
PTEN loss prostate
prostate cancer biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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