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Translational Medicine / 转化医学Epigenome Computational Biology

Michael Hoffman

MD

🏢Princess Margaret Cancer Centre🌐Canada

Senior Scientist

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Key Contributions

👥Biography 个人简介

Michael Hoffman at Princess Margaret Cancer Centre is a computational biologist specializing in cancer epigenomics. His Segway algorithm for segmenting the genome into functional elements using multi-track epigenomic data has been applied extensively to cancer epigenome analysis. His contributions to ENCODE project computational methods and his research on cancer-specific chromatin accessibility patterns have advanced understanding of regulatory element dysregulation in cancer.

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🧪Research Fields 研究领域

cancer epigenomics
chromatin accessibility
DNA methylation patterns
ENCODE project
computational epigenomics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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