Michael Heinrich
MD
Professor of Medicine and Cell and Developmental Biology
👥Biography 个人简介
Dr. Michael Heinrich is a co-discoverer of imatinib's activity in GIST and a world-leading expert on KIT and PDGFRA kinase biology in this disease. He characterized the secondary KIT resistance mutations that emerge on imatinib and was instrumental in developing avapritinib for PDGFRA D842V-mutant GIST -- a mutation previously unresponsive to all approved therapies. His molecular insights have guided all subsequent GIST drug development.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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