Michael Crump
迈克尔·克伦普
MD, FRCPC
Professor of Medicine, University of Toronto; Medical Oncologist, Lymphoma Program多伦多大学医学教授；淋巴瘤项目肿瘤内科医师
👥Biography 个人简介
Michael Crump, MD, FRCPC is a medical oncologist at the Princess Margaret Cancer Centre and Professor at the University of Toronto. He co-led the international SCHOLAR-1 study, which comprehensively characterized the dismal outcomes of relapsed/refractory DLBCL, establishing the benchmark that drove development of CAR-T and bispecific therapies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
SCHOLAR-1 — Relapsed/Refractory DLBCL Benchmark
Co-led SCHOLAR-1, a pooled analysis of 636 patients defining objective response rate of 26% and median OS of 6.3 months with salvage therapy in r/r DLBCL, establishing the urgent unmet need benchmark.
Lymphoma Cooperative Trial Leadership in Canada
Led multiple NCIC CTG and ECOG lymphoma trials evaluating novel salvage regimens, R-GDP, and autologous transplant outcomes in Canadian and international DLBCL cohorts.
Representative Works 代表性著作
Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study
Blood (2017)
Pooled analysis across four cohorts defining the poor prognosis of refractory DLBCL and providing the key historical control for emerging CAR-T therapies.
Gemcitabine, dexamethasone, and cisplatin for relapsed or refractory aggressive histology B-cell non-Hodgkin lymphoma
Journal of Clinical Oncology (2004)
Phase II trial establishing GDP as an active and less toxic salvage regimen for relapsed/refractory aggressive B cell lymphoma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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