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Translational Medicine / 转化医学NK Cell Therapy, NK Cell Biology

Michael A. Caligiuri

MD

🏢City of Hope National Medical Center🌐USA

President, City of Hope National Medical Center

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👥Biography 个人简介

Michael Caligiuri is a distinguished NK cell biologist and cancer leader who has made seminal contributions to understanding NK cell development, differentiation, and anti-tumor function. His laboratory established key roles for cytokines including IL-15 and IL-21 in NK cell homeostasis and function. He characterized the molecular mechanisms of NK cell activation and tolerance to normal cells. As President of City of Hope, he continues to foster development of NK cell and other cellular therapies. He has trained dozens of NK cell researchers and is widely recognized as a founding figure in NK cell immunotherapy.

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🧪Research Fields 研究领域

NK cell biology fundamentals
NK cell development
large granular lymphocyte leukemia
innate lymphocyte cancer immunity
NK cell signaling pathways

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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