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Cell Therapy / 细胞治疗Lymphoma

Michael R. Bishop

迈克尔·毕晓普

MD

🏢University of Chicago Medicine(芝加哥大学医学中心)🌐USA

Professor of Medicine; Director, Hematopoietic Cellular Therapy Program医学教授;造血细胞治疗项目主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Dr. Michael R. Bishop is a leading expert in CAR-T cell therapy for aggressive B-cell lymphomas. He was a principal investigator in the ZUMA-1 pivotal trial of axicabtagene ciloleucel (axi-cel) for relapsed/refractory DLBCL, which established CAR-T as a standard-of-care option.

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🧪Research Fields 研究领域

Diffuse Large B-Cell Lymphoma弥漫大B细胞淋巴瘤
CAR-T Cell TherapyCAR-T细胞治疗
Hematopoietic Stem Cell Transplantation造血干细胞移植

🎓Key Contributions 主要贡献

ZUMA-1 Trial Leadership

Served as key investigator in the landmark ZUMA-1 trial demonstrating durable remissions with axi-cel CAR-T in relapsed/refractory DLBCL, leading to FDA approval and transforming treatment paradigms.

Representative Works 代表性著作

[1]

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

New England Journal of Medicine (2017)

Pivotal ZUMA-1 results showing 54% objective response rate with axi-cel in refractory DLBCL, establishing CAR-T as a viable salvage therapy.

🏆Awards & Recognition 奖项与荣誉

🏆American Society of Hematology Recognition Award
🏆University of Chicago Distinguished Clinician Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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