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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

Ignacio Melero

MD, PhD

🏢University of Navarra / CIMA🌐Spain

Professor of Immunology and Director, Immunology and Immunotherapy Program

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👥Biography 个人简介

Ignacio Melero is a leading cancer immunologist who has developed intratumoral strategies using co-stimulatory agonist antibodies and immunostimulatory cytokines to reprogram the tumor immune microenvironment. His work on intratumoral anti-CD137 and IL-12 approaches has advanced to clinical trials demonstrating local and systemic immune activation. He has contributed fundamental insights into how intratumoral treatments reshape anti-tumor immune responses.

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🧪Research Fields 研究领域

Intratumoral immunostimulation
CD137 agonist intratumoral
Combination intratumoral IO
Tumor immune microenvironment
Cancer immunology translation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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