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Translational Medicine / 转化医学Fragmentomics, ctDNA in Lung Cancer

Maximilian Diehn

MD, PhD

🏢Stanford University School of Medicine🌐USA

Associate Professor, Radiation Oncology

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Key Contributions

👥Biography 个人简介

Maximilian Diehn at Stanford developed CAPP-Seq, a highly sensitive targeted sequencing approach for ctDNA detection in lung cancer and lymphoma. His laboratory pioneered fragmentomics-based cancer detection using cell-free DNA size and fragmentation patterns. He has translated ctDNA MRD monitoring into radiation oncology settings, demonstrating that post-treatment ctDNA predicts relapse after curative-intent radiotherapy.

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🧪Research Fields 研究领域

fragmentomics ctDNA
CAPP-Seq liquid biopsy
lung cancer ctDNA
ctDNA MRD after radiotherapy
plasma cell-free DNA profiles

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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