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Translational Medicine / 转化医学CDK12 Synthetic Lethality

David Mauro

MD, PhD

🏢Aurigene Oncology🌐USA

Chief Medical Officer

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Key Papers
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Key Contributions

👥Biography 个人简介

David Mauro leads clinical development of novel CDK12 and CDK13 inhibitors for cancers harboring DNA damage repair defects. His work translates synthetic lethal targeting of CDK12 altered tumors into early phase trials across prostate and ovarian cancers. He has a strong background in molecular oncology and translational development of precision therapies.

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🧪Research Fields 研究领域

CDK12
synthetic lethality
DNA damage response
targeted therapy
clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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