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Translational Medicine / 转化医学Cancer Metabolism Milestones, Pyruvate Kinase and Tumor Metabolism

Matthew Vander Heiden

MD, PhD

🏢Massachusetts Institute of Technology🌐USA

Director, Koch Institute for Integrative Cancer Research

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Key Contributions

👥Biography 个人简介

Matthew Vander Heiden defined the role of PKM2 in tumor anabolic metabolism and reframed the Warburg effect for the modern era. His work integrates biochemistry, metabolomics, and cancer cell biology. He directs one of the leading cancer research centers in the United States.

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🧪Research Fields 研究领域

PKM2
pyruvate kinase
anabolic metabolism
tumor proliferation
metabolomics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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