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Translational Medicine / 转化医学Follicular Lymphoma, EZH2 and Tazemetostat

Matthew Lunning

DO

🏢University of Nebraska Medical Center🌐USA

Associate Professor of Internal Medicine, Oncology and Hematology

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Key Contributions

👥Biography 个人简介

Matthew Lunning is a lymphoma specialist who has contributed to clinical development of tazemetostat, an EZH2 inhibitor approved for relapsed/refractory follicular lymphoma with EZH2 mutations and as a later-line option for wild-type EZH2 disease. His work evaluates predictive biomarkers for EZH2 inhibitor activity and combinations with anti-CD20 antibodies. He studies epigenetic mechanisms of lymphomagenesis and resistance to targeted epigenetic therapies. He is active in SWOG and other cooperative group lymphoma trials.

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🧪Research Fields 研究领域

tazemetostat EZH2 follicular lymphoma
EZH2 mutations FL
epigenetic therapy lymphoma
E7438 tazemetostat
EZH2 inhibitor clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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