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Translational Medicine / 转化医学Lung Cancer, KRAS G12C

Matthew Gowen

MD

🏢University of Texas Southwestern Medical Center🌐USA

Medical Oncologist, Thoracic and GI Oncology

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Key Contributions

👥Biography 个人简介

Dr. Matthew Gowen is a medical oncologist investigating KRAS G12C-targeted therapy across tumor types including lung, colorectal, and pancreatic cancer. He has participated in pan-tumor basket trials evaluating adagrasib in KRAS G12C-mutant solid tumors beyond lung cancer. His research focuses on identifying predictors of response and resistance in the pan-tumor setting and on evaluating SHP2 plus KRAS G12C inhibitor combinations.

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🧪Research Fields 研究领域

KRAS G12C pan-tumor
KRAS pancreatic
KRAS colorectal
SHP2 plus KRAS inhibitor
KRAS combination clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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