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Translational Medicine / 转化医学Molecular Subtypes HR+ Breast

Matthew Ellis

MB, BChir, PhD

🏢Baylor College of Medicine🌐USA

Director, Lester and Sue Smith Breast Center

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Key Contributions

👥Biography 个人简介

Matthew Ellis at Baylor College of Medicine has defined molecular subtypes of hormone receptor-positive breast cancer and their implications for treatment selection. He led pivotal studies on neoadjuvant aromatase inhibitor therapy and comprehensive genomic analyses of luminal breast cancers through TCGA. His work on ESR1 mutations as drivers of endocrine resistance has been transformative for the field.

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🧪Research Fields 研究领域

molecular subtypes HR+ breast
ESR1 mutations
luminal A and B classification
neoadjuvant aromatase inhibitors
breast cancer genomics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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