Mathias Chamaillard

Mathias Chamaillard investigates the role of innate immune sensing of gut microbiota in cancer development and treatment response. His laboratory has characterized how NOD-like receptors detect bacterial components and how these signals modulate anti-tumor immunity and chemotherapy responses. He has contributed to understanding how specific bacteria impact colorectal cancer development and how microbiome composition influences the efficacy of chemotherapy and immunotherapy through innate immune activation. His work bridges mucosal immunology with cancer biology.