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Translational Medicine / 转化医学ESR1 Mutations, Circulating Tumor Cells

Massimo Cristofanilli

MD

🏢Northwestern University, Robert H. Lurie Comprehensive Cancer Center🌐USA

Associate Director for Translational Research

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Key Contributions

👥Biography 个人简介

Massimo Cristofanilli is a translational researcher at Northwestern who has championed the clinical use of circulating tumor cells and liquid biopsy in metastatic breast cancer. He has contributed to understanding ESR1 mutations as drivers of acquired endocrine resistance and to the development of novel selective estrogen receptor proteolysis-targeted therapies. His work integrates liquid biopsy biomarkers with treatment selection.

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🧪Research Fields 研究领域

ESR1 mutations endocrine resistance
elacestrant SERP
circulating tumor cells
liquid biopsy breast
metastatic HR+ breast

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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