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Translational Medicine / 转化医学BRCA1 Discovery, Hereditary Cancer Genetics

Mary-Claire King

PhD

🏢University of Washington🌐USA

American Cancer Society Professor of Genome Sciences and Medicine

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Key Contributions

👥Biography 个人简介

Mary-Claire King mapped BRCA1 to chromosome 17q21, proving the existence of a hereditary breast cancer gene and launching the era of cancer genetic testing. Her advocacy for population-wide BRCA screening has transformed cancer prevention. She demonstrated that a single gene could account for a significant fraction of breast and ovarian cancer risk, establishing the foundation for precision prevention in oncology.

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🧪Research Fields 研究领域

BRCA1 discovery
hereditary breast cancer
cancer genetic testing
population screening BRCA
human genetics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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