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Translational Medicine / 转化医学MCL-1 Targeting, Myeloma Apoptosis

Martin Bhatt

MD PhD

🏢Mayo Clinic🌐USA

Associate Professor of Oncology

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Key Contributions

👥Biography 个人简介

Martin Bhatt focuses on MCL-1 as a critical survival factor in multiple myeloma and other cancers resistant to BCL-2 inhibition. His BH3 profiling studies have defined which BCL-2 family members specific cancer subtypes depend upon, enabling precision selection of BH3-mimetic therapy. He has investigated combination strategies pairing MCL-1 inhibitors with venetoclax to overcome apoptosis resistance. His clinical research aims to translate BH3-mimetic combinations into myeloma practice.

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🧪Research Fields 研究领域

MCL-1 inhibitors
multiple myeloma apoptosis
BH3 profiling
drug resistance
venetoclax combination

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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