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Translational Medicine / 转化医学Gastric Cancer, CHECKMATE-649 Nivolumab

Markus Moehler

MD

🏢University Medical Center Mainz🌐Germany

Professor of Internal Medicine

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Key Contributions

👥Biography 个人简介

Markus Moehler at University Medical Center Mainz was the lead investigator of the CHECKMATE-649 trial establishing nivolumab plus chemotherapy as first-line standard of care for HER2-negative advanced gastric and GEJ cancer, a practice-changing result. His research on perioperative FLOT regimen in resectable gastric cancer and combined modality approaches has contributed to early-stage gastric cancer management. He has been a key European leader in gastric cancer clinical research and contributes to ESMO guidelines. His work bridges surgical, perioperative, and advanced disease management in gastric and GEJ cancers.

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🧪Research Fields 研究领域

CHECKMATE-649 nivolumab gastric
nivolumab chemotherapy first-line gastric
gastric cancer immunotherapy Europe
FLOT gastric perioperative
gastroesophageal junction combined modality

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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