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Translational Medicine / 转化医学T-Cell Lymphoma, HDAC Inhibitors

Mark Roschewski

MD

🏢National Cancer Institute (NCI)🌐USA

Senior Clinician, Lymphoid Malignancies Branch

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Key Contributions

👥Biography 个人简介

Mark Roschewski at the NCI has contributed to clinical investigations of romidepsin and belinostat — two HDAC inhibitors approved for relapsed/refractory PTCL — and studied mechanisms of response and resistance in T-cell lymphoma. His research at the NCI encompasses clinical trial design, biomarker development, and combination strategies for T-cell malignancies. He is an important voice on lymphoma clinical trial endpoints.

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🧪Research Fields 研究领域

romidepsin PTCL
HDAC inhibitors T-cell lymphoma
belinostat
histone deacetylase therapy
NCI lymphoma trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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