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Translational Medicine / 转化医学Tumor Hypoxia, Radiation Biology

Mark Dewhirst

DVM, PhD

🏢Duke University Medical Center🌐USA

Gustavo S. Montana Distinguished Professor Emeritus of Radiation Oncology

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👥Biography 个人简介

Dr. Mark Dewhirst is a radiation biology pioneer whose research has fundamentally shaped understanding of how tumor hypoxia causes radiation resistance. He conducted landmark studies on tumor oxygenation dynamics and developed hyperthermia as a strategy to sensitize hypoxic tumors to radiation. His four decades of research have provided mechanistic insights into the tumor microenvironment factors governing radiation response.

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🧪Research Fields 研究领域

tumor hypoxia radiation resistance
hyperthermia radiation combination
angiogenesis radiation response
HIF-1 radiation biology
oxygenation tumor response

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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