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Translational Medicine / 转化医学T Cell Receptor Discovery, Cancer Immunosurveillance

Mark Davis

MD

🏢Stanford University School of Medicine🌐USA

Professor of Microbiology and Immunology

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Key Contributions

👥Biography 个人简介

Mark Davis at Stanford discovered and cloned the alpha-beta T cell receptor, one of the landmark discoveries in immunology that defined how T cells recognize antigens. His subsequent development of MHC-peptide tetramer technology for identifying and tracking antigen-specific T cells in cancer patients has been a critical tool for immune monitoring in cancer immunotherapy trials. His contributions span from fundamental TCR biology to clinical cancer immunology.

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🧪Research Fields 研究领域

T cell receptor discovery
alpha-beta TCR cloning
MHC-peptide tetramers
TCR diversity cancer
immune monitoring

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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