Learn more →
Back to Expert Scholars
Translational Medicine / 转化医学Cyclodextrin Nanoparticles, siRNA Delivery

Mark Davis

MD

🏢California Institute of Technology🌐USA

Warren and Katharine Schlinger Professor

82
h-index
0
Key Papers
0
Key Contributions

👥Biography 个人简介

Mark Davis at Caltech developed cyclodextrin-based nanoparticles (CALAA-01) for targeted siRNA delivery — the first nanoparticle-delivered siRNA construct to enter human clinical trials. His demonstration of siRNA tumor delivery in humans using transferrin-targeted CALAA-01 particles established proof of mechanism for targeted RNAi in cancer. His contributions to polymer chemistry and nanoparticle design have advanced the cancer nanomedicine field.

Share:

🧪Research Fields 研究领域

cyclodextrin nanoparticles
siRNA cancer
RRM2 siRNA
transferrin-targeted nanoparticles
first human siRNA trial

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

关注 Mark Davis 的研究动态

Follow Mark Davis's research updates

留下邮箱,当我们发布与 Mark Davis(California Institute of Technology)相关的新研究或访谈时,我们会通知你。

我们不会泄露你的信息,也不会发送无关内容。随时可以退订。

Explore More Experts

Discover the researchers shaping the future of cancer treatment