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Translational Medicine / 转化医学Immunotherapy Biomarkers, TMB, MSI

Mark Bhatt

MD, PhD

🏢Johns Hopkins School of Medicine🌐USA

Associate Professor of Oncology

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👥Biography 个人简介

Mark Bhatt specializes in biomarker development for immunotherapy response prediction at Johns Hopkins, with expertise in tumor mutational burden and microsatellite instability. His research has contributed to the analytical and clinical validation of TMB as a predictive biomarker for checkpoint inhibitor therapy across tumor types. He evaluated the concordance between tissue and liquid biopsy TMB assessments and their clinical utility. His work advances the field of precision immunooncology by identifying which patients will benefit most from checkpoint inhibitors.

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🧪Research Fields 研究领域

tumor mutational burden
microsatellite instability
immunotherapy biomarkers
PD-L1 testing
cfDNA biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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