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Translational Medicine / 转化医学KRAS, RAS Biology

Mariano Barbacid

MD

🏢Centro Nacional de Investigaciones Oncologicas (CNIO)🌐Spain

Director, Molecular Oncology Programme

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Key Contributions

👥Biography 个人简介

Mariano Barbacid discovered the first human cancer gene (RAS) in 1982 through transforming DNA assays, a landmark discovery that launched the field of oncogene biology. He subsequently made foundational contributions to RAS biology, CDK4/6 biology, and cancer mouse models. He now directs the Molecular Oncology Programme at CNIO in Madrid, continuing work on KRAS targeting strategies.

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🧪Research Fields 研究领域

KRAS
RAS oncogenes
mouse models
KRAS G12C inhibitors
cancer genetics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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