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Translational Medicine / 转化医学CAR-T Cell Therapy, Resistance Mechanisms

Marco Ruella

MD

🏢University of Pennsylvania🌐USA

Assistant Professor of Medicine

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Key Contributions

👥Biography 个人简介

Marco Ruella at the University of Pennsylvania is an expert in CAR-T cell therapy resistance and manufacturing optimization. His research has characterized mechanisms of CD19 antigen loss in B cell malignancies, identified strategies to prevent antigen escape, and contributed to advances in CAR-T manufacturing including selection for less differentiated T cell subsets with enhanced persistence.

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🧪Research Fields 研究领域

CAR-T cell therapy
resistance mechanisms
antigen escape
CAR-T manufacturing
lymphoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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