Marco Ruella
MD
Assistant Professor of Hematology-Oncology
👥Biography 个人简介
Marco Ruella at the University of Pennsylvania investigates mechanisms of CAR-T therapy resistance and next-generation CAR engineering strategies. He has characterized CD19 antigen escape as a primary mechanism of relapse after CD19 CAR-T therapy and developed approaches to overcome it. His recent work explores in vivo CAR-T generation using nanoparticle gene delivery to circumvent manufacturing barriers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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