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Translational Medicine / 转化医学Tumor Suppressor Biology, NF2

Marco Giovannini

MD, PhD

🏢House Ear Institute / UCLA Medical Center🌐USA

Director, Laboratory of Neural Tumor Biology

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👥Biography 个人简介

Marco Giovannini is a specialist in NF2 (neurofibromatosis type 2) and the merlin tumor suppressor protein encoded by the NF2 gene. His research has defined how merlin loss promotes schwannoma, meningioma, and ependymoma formation, and demonstrated connections between merlin and the Hippo/YAP signaling pathway. He contributed to mouse models of NF2-associated tumors that have been used to test targeted therapies. His translational work is developing therapeutic approaches for NF2-deficient cancers including mesothelioma.

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🧪Research Fields 研究领域

NF2 neurofibromatosis type 2
merlin tumor suppressor
schwannoma biology
mesothelioma NF2
hippo pathway YAP

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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