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hematopoietic-transplant / hematopoietic-transplantCAR-T Cell Therapy

Marcelo C. Pasquini

马塞洛·帕斯奎尼

MD, MS

🏢Medical College of Wisconsin / Froedtert Hospital(威斯康星医学院/弗罗德特医院)🌐USA

Professor of Medicine; Director, Cellular Therapy Program; CIBMTR Statistician医学教授,细胞治疗项目主任,CIBMTR统计学家

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Marcelo Pasquini is a leading physician-scientist in cellular therapy and transplant outcomes research, combining clinical expertise with sophisticated registry-based analyses through the CIBMTR. His work on real-world CAR-T cell therapy outcomes has been pivotal in demonstrating effectiveness beyond controlled trials and guiding access policies.

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🧪Research Fields 研究领域

CAR-T OutcomesCAR-T细胞治疗结局
CIBMTR Registry ResearchCIBMTR注册研究
HSCT造血干细胞移植
Cellular Therapy细胞治疗

🎓Key Contributions 主要贡献

Real-World CAR-T Cell Therapy Outcomes

Led landmark CIBMTR registry studies characterizing outcomes of axicabtagene ciloleucel and tisagenlecleucel in real-world patients, validating efficacy observed in clinical trials.

CIBMTR Registry Science

Advanced methodological frameworks for analyzing transplant and cellular therapy registry data, enabling population-level insights that inform clinical guidelines and payer decisions.

Cord Blood and Alternative Donor Transplantation

Conducted pivotal studies comparing cord blood to other alternative donor sources, informing donor selection when matched siblings or unrelated donors are unavailable.

Representative Works 代表性著作

[1]

Outcomes of patients with large B-cell lymphoma treated with standard of care axicabtagene ciloleucel in the United States

Blood Advances (2022)

First large-scale US real-world analysis of axi-cel outcomes, confirming effectiveness in diverse patient populations outside trial settings.

[2]

Outcome of patients with hematological malignancies and COVID-19 receiving COVID-19-directed therapy: a report from the ASH-RC COVID-19 Registry

Blood Advances (2021)

Characterized outcomes of transplant and cellular therapy recipients with COVID-19 at the height of the pandemic.

[3]

Transplantation outcomes for acute leukemia following umbilical cord blood or bone marrow from unrelated donors

Annals of Internal Medicine (2010)

Seminal registry comparison demonstrating comparable leukemia-free survival for cord blood vs. bone marrow unrelated donor transplants.

🏆Awards & Recognition 奖项与荣誉

🏆American Society for Transplantation and Cellular Therapy Outstanding Abstract Award
🏆Medical College of Wisconsin Scholar Award
🏆CIBMTR Scientific Achievement Recognition

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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