Marcela V. Maus
M.D., Ph.D.
Director, Cellular Immunotherapy Program
👥Biography 个人简介
Marcela Maus is a leader in developing CAR-T cell therapies for solid tumors, with particular focus on glioblastoma and other brain tumors. Her laboratory has pioneered local delivery of CAR-T cells to the central nervous system and developed novel CAR designs to overcome the immunosuppressive tumor microenvironment. Maus is advancing multiple CAR-T clinical trials at MGH.
Marcela Maus是开发实体肿瘤CAR-T细胞治疗的领导者,特别关注胶质母细胞瘤和其他脑肿瘤。她的实验室开创了CAR-T细胞向中枢神经系统的局部递送,并开发了克服免疫抑制性肿瘤微环境的新型CAR设计。Maus正在MGH推进多项CAR-T临床试验。
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
GBM CAR-T
Developing CAR-T approaches for glioblastoma with local CNS delivery.
CAR Engineering
Novel CAR designs incorporating safety switches and armoring strategies.
Representative Works 代表性著作
CAR T Cell Therapy for Glioblastoma: Lessons Learned from the First Clinical Trial
Clinical Cancer Research (2020)
Insights from first GBM CAR-T trial.
📄Data Sources 数据来源
Last updated: 2026-03-04 | All information from publicly available academic sources
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