Mafalda Oliveira

Mafalda Oliveira is a clinical investigator specializing in endocrine resistance mechanisms in HR+ breast cancer, with a particular focus on ESR1 mutations as drivers of resistance to aromatase inhibitors. She has been a principal investigator on trials of oral SERDs including elacestrant and amcenestrant and has contributed to understanding ctDNA dynamics as a monitoring tool. Her research links molecular mechanisms of ESR1 mutation with clinical behavior and therapeutic implications. She is an emerging leader in the field of endocrine resistance and novel targeting strategies.