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Translational Medicine / 转化医学Cancer RNA Biology

Lynda Chin

陈丽达

MD

🏢UTHealth Houston / The University of Texas MD Anderson Cancer Center(德克萨斯大学休斯顿健康科学中心/MD安德森癌症中心)🌐USA

Professor and Chief Strategy Officer for Health Transformation; Former Scientific Director, Institute for Applied Cancer Science教授及健康转型首席战略官;前应用癌症科学研究所科学主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Architect of large-scale cancer transcriptomics and co-leader of The Cancer Genome Atlas (TCGA). Integrates RNA and genomic data to decode cancer biology and translate findings into clinical precision oncology platforms.

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🧪Research Fields 研究领域

Cancer Genome and Transcriptome癌症基因组与转录组
Melanoma Molecular Oncology黑色素瘤分子肿瘤学
TCGA Cancer AtlasTCGA癌症图谱
Oncology Informatics肿瘤信息学
Precision Oncology精准肿瘤学

🎓Key Contributions 主要贡献

TCGA Cancer Genome Atlas

Co-led TCGA project generating comprehensive multi-omic including RNA-seq profiles of 33 cancer types, creating a foundational resource transforming cancer biology.

Melanoma Transcriptomics

Defined molecular subtypes of melanoma through integrated genomic and transcriptomic analysis, identifying oncogenic drivers and therapeutic vulnerabilities.

Representative Works 代表性著作

[1]

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature (2008)

Landmark TCGA GBM paper integrating genome-wide RNA and DNA profiling to define GBM molecular architecture.

[2]

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

New England Journal of Medicine (2013)

Comprehensive AML molecular atlas including transcriptomic data guiding precision therapy.

[3]

The somatic genomic landscape of chromophobe renal cell carcinoma

Cancer Cell (2014)

TCGA characterization of chromophobe RCC revealing RNA expression subtypes.

🏆Awards & Recognition 奖项与荣誉

🏆NCI Outstanding Investigator Award
🏆Forbes Healthcare Innovator
🏆AAAS Fellow

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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