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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

Jason Luke

MD

🏢UPMC Hillman Cancer Center🌐USA

Associate Professor of Medicine and Director of Cancer Immunotherapeutics Center

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👥Biography 个人简介

Jason Luke has conducted pivotal clinical trials of intratumoral STING agonists and other innate immune activators for melanoma and solid tumors. His research on combining intratumoral innate immune stimulation with systemic checkpoint blockade has informed rational combination strategies. He has advanced biomarker-driven approaches to identifying patients most likely to benefit from intratumoral immunotherapy.

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🧪Research Fields 研究领域

STING agonist clinical trials
Intratumoral combination therapy
Melanoma immunotherapy
Innate immune activation
Biomarker-driven IO selection

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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