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Translational Medicine / 转化医学SCLC Immunotherapy, Atezolizumab IMpower133

Luis Paz-Ares

MD, PhD

🏢Hospital Universitario 12 de Octubre / CNIO🌐Spain

Professor and Head, Medical Oncology Department

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Key Contributions

👥Biography 个人简介

Luis Paz-Ares is the principal investigator of the IMpower133 trial that established atezolizumab plus carboplatin-etoposide as a standard of care for extensive-stage SCLC, achieving the first survival improvement in this setting in over two decades. He has led pivotal trials in NSCLC and SCLC across multiple histologies and molecular subtypes. His research program spans novel immunotherapy combinations, biomarker development, and treatment resistance in thoracic oncology. He is a key author of ESMO lung cancer guidelines and the most cited thoracic oncologist in Spain.

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🧪Research Fields 研究领域

IMpower133 trial extensive SCLC atezolizumab
SCLC first-line immunotherapy combinations
SCLC platinum-etoposide backbone
lung cancer drug development Europe
ESMO lung cancer guidelines

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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