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Translational Medicine / 转化医学Myeloproliferative Neoplasms, Navitoclax Combinations

Lucia Masarova

MD

🏢University of Texas MD Anderson Cancer Center🌐USA

Assistant Professor, Department of Leukemia

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Key Contributions

👥Biography 个人简介

Lucia Masarova is an emerging MPN expert at MD Anderson whose clinical research focuses on combination strategies to achieve deeper molecular responses in myelofibrosis. She has contributed to pivotal trials evaluating navitoclax (BCL-XL/BCL-2 inhibitor) in combination with ruxolitinib for myelofibrosis, including the TRANSFORM-1 trial. Her work explores whether navitoclax combinations can achieve clonal reduction and disease modification beyond symptom control. She actively investigates biomarkers predicting response to these novel combinations.

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🧪Research Fields 研究领域

navitoclax myelofibrosis
BCL-XL inhibition MPN
ruxolitinib plus navitoclax
TRANSFORM trial
clonal reduction myelofibrosis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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