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Translational Medicine / 转化医学Pancreatic Cancer KRAS

Scott Lowe

PhD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Chair, Cancer Biology and Genetics Program

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Key Contributions

👥Biography 个人简介

Scott Lowe has made landmark discoveries in tumor suppression, apoptosis, and how cooperating mutations with KRAS drive pancreatic cancer progression. His innovative in vivo RNAi and CRISPR screening approaches have identified critical genetic dependencies in KRAS-mutant pancreatic cancer. His work has been transformative for understanding treatment resistance mechanisms.

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🧪Research Fields 研究领域

Tumor suppressor genes
Apoptosis
KRAS cooperating mutations
In vivo RNAi screens
Senescence

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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