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Translational Medicine / 转化医学Thyroid Cancer

Lori Wirth

洛里·沃思

MD

🏢Massachusetts General Hospital(麻省总医院)🌐USA

Associate Professor of Medicine, Harvard Medical School哈佛医学院医学副教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Leading expert in RAI-refractory thyroid cancer and systemic therapy. Pioneered the use of lenvatinib and RET/NTRK inhibitors in differentiated thyroid cancer. Has led major clinical trials establishing the standard of care for advanced thyroid malignancies.

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🧪Research Fields 研究领域

Thyroid Cancer甲状腺癌
RET InhibitorsRET抑制剂
Differentiated Thyroid Cancer分化型甲状腺癌

🎓Key Contributions 主要贡献

RAI-Refractory Thyroid Cancer

Led seminal clinical investigations of lenvatinib in radioiodine-refractory differentiated thyroid cancer, contributing to its FDA approval and establishing lenvatinib as a first-line standard of care.

Representative Works 代表性著作

[1]

Lenvatinib versus placebo in radioiodine-refractory thyroid cancer

New England Journal of Medicine (2015)

SELECT trial demonstrating significant progression-free survival benefit with lenvatinib in RAI-refractory differentiated thyroid cancer.

🏆Awards & Recognition 奖项与荣誉

🏆American Thyroid Association Distinguished Service Award
🏆ASCO Merit Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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