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Translational Medicine / 转化医学Cancer Base and Prime Editing

David Liu

PhD

🏢Broad Institute of MIT and Harvard🌐USA

Richard Merkin Professor; Director, Merkin Institute of Transformative Technologies in Healthcare

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Key Contributions

👥Biography 个人简介

David Liu invented base editing and prime editing, which enable precise single nucleotide changes without double-strand DNA breaks. These technologies have become foundational for engineering T cells and correcting cancer-associated point mutations. He co-founded Beam Therapeutics and Prime Medicine to translate these tools into therapies.

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🧪Research Fields 研究领域

base editing
prime editing
cytidine deaminase
adenine base editing
precise cancer gene correction

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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