Lisa Bhatt

Lisa Bhatt uses liquid biopsy and circulating tumor DNA analysis to track tumor clonal evolution non-invasively during cancer treatment. Her research has demonstrated that serial ctDNA analysis can reveal the emergence of resistant subclones weeks before radiographic progression. She has developed methods for tracking multiple co-existing cancer subclones through treatment using plasma DNA. Her work establishes ctDNA as a window into tumor evolutionary dynamics and a tool for early resistance detection and treatment adaptation.