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Translational Medicine / 转化医学Neuro-Oncology, GBM Vaccines Immunotherapy

Linda Liau

MD, PhD, MBA

🏢University of California, Los Angeles🌐USA

Professor and Chair, Department of Neurosurgery

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Key Contributions

👥Biography 个人简介

Linda Liau led the development and clinical investigation of DCVax-L, a dendritic cell-based vaccine for GBM, and was principal investigator on the landmark phase III trial reporting extended overall survival benefit in MGMT-methylated patients. Her research spans tumor immunology, surgical management, and biomarker identification for GBM immunotherapy response. She has contributed to understanding the immunosuppressive tumor microenvironment in GBM.

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🧪Research Fields 研究领域

GBM dendritic cell vaccine
GBM immunotherapy DCVax-L
MGMT methylation immunotherapy
GBM antigen-specific therapy
neuro-oncology surgical outcomes

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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