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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

Ronald Levy

MD

🏢Stanford University🌐USA

Robert K. and Helen K. Summy Professor of Medicine

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Key Contributions

👥Biography 个人简介

Ronald Levy is the originator of the CpG plus anti-OX40 intratumoral in situ vaccination approach that has demonstrated remarkable systemic responses from local treatment in lymphoma. His pioneering work showed that injecting TLR9 agonists directly into tumors combined with T cell co-stimulation can eradicate distant metastases through abscopal immunity. He is widely regarded as the father of modern in situ cancer vaccination.

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🧪Research Fields 研究领域

CpG plus anti-OX40 vaccination
Intratumoral TLR9 agonist
Lymphoma in situ vaccination
Abscopal immune responses
Anti-idiotype antibody therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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