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Translational Medicine / 转化医学Telomerase Biology, Cancer

Lea Harrington

PhD

🏢Universite de Montreal🌐Canada

Professor, Institute for Research in Immunology and Cancer

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Key Contributions

👥Biography 个人简介

Lea Harrington has made significant contributions to understanding the biochemistry of telomerase and its role in cancer. She characterized essential components of the telomerase holoenzyme and demonstrated how telomere dysfunction promotes genomic instability in cancer cells. Her mouse models of telomerase deficiency revealed connections between telomere shortening and cancer predisposition. She has also studied how telomerase is regulated during development and malignant transformation.

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🧪Research Fields 研究领域

telomerase complex
TERT
TERC
telomere cancer mouse models
hematologic malignancies

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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