Lawrence Marks
劳伦斯·马克斯
MD
Lineberger Professor and Chair of Radiation Oncology莱恩伯格放射肿瘤学教授兼主任
👥Biography 个人简介
Lawrence Marks is a world leader in understanding and mitigating radiation-induced late effects, particularly cardiac toxicity in breast cancer patients. His quantitative normal tissue complication modeling and clinical research have reshaped radiotherapy planning to minimize long-term morbidity.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Cardiac Toxicity in Breast Radiotherapy
Quantified the relationship between cardiac radiation dose and long-term cardiac events in breast cancer patients, providing dose-volume constraints now incorporated into international guidelines.
QUANTEC Normal Tissue Guidelines
Led the QUANTEC initiative that systematically reviewed dose-volume relationships for organs at risk, producing widely adopted constraints guiding safe radiotherapy planning worldwide.
Representative Works 代表性著作
QUANTEC: an updated model of normal tissue complication probability
International Journal of Radiation Oncology Biology Physics (2010)
Landmark review synthesizing dose-volume toxicity data across organs, establishing evidence-based normal tissue constraints for radiation treatment planning.
Cardiac effects of breast cancer radiotherapy
Journal of Clinical Oncology (2016)
Demonstrated clinically significant cardiac dose-response relationships in breast cancer survivors, informing cardiac-sparing radiotherapy techniques.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Brian Marples
University of Rochester Medical Center
Silvia C. Formenti
Weill Cornell Medicine / NewYork-Presbyterian Hospital
Paul M. Harari
University of Wisconsin School of Medicine and Public Health
Jeff Forman
Wayne State University / Karmanos Cancer Institute
关注 劳伦斯·马克斯 的研究动态
Follow Lawrence Marks's research updates
留下邮箱，当我们发布与 Lawrence Marks（University of North Carolina at Chapel Hill）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment