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Translational Medicine / 转化医学T-DXd Breast Cancer

Ian Krop

MD, PhD

🏢Yale Cancer Center🌐USA

Chief of Breast Medical Oncology

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Key Contributions

👥Biography 个人简介

Ian Krop is a leading breast oncologist who has been central to the clinical development of trastuzumab deruxtecan and other ADCs for breast cancer. He has led key DESTINY-Breast trials and contributed to defining optimal treatment sequencing for HER2-positive disease. His translational research on resistance mechanisms informs next-generation therapeutic strategies.

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🧪Research Fields 研究领域

Breast cancer
HER2-targeted therapy
Trastuzumab deruxtecan
ADC development
PI3K pathway

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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