Learn more →
Back to Expert Scholars
Translational Medicine / 转化医学Histone Methylation, Polycomb Repressive Complexes

Kristian Helin

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Director

72
h-index
0
Key Papers
0
Key Contributions

👥Biography 个人简介

Kristian Helin at MSK is a world authority on Polycomb repressive complex (PRC) biology and histone methylation in cancer. His extensive work characterizing how Polycomb complexes PRC1 and PRC2 regulate gene expression through H3K27 methylation and H2A ubiquitination has informed the development of EZH2 inhibitors (tazemetostat) for EZH2-mutated B cell lymphoma and INI1-deficient malignancies like epithelioid sarcoma.

Share:

🧪Research Fields 研究领域

Polycomb repressive complexes
EZH2 inhibitors
PRC2
histone H3K27 methylation
epigenetic cancer targets

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

关注 Kristian Helin 的研究动态

Follow Kristian Helin's research updates

留下邮箱,当我们发布与 Kristian Helin(Memorial Sloan Kettering Cancer Center)相关的新研究或访谈时,我们会通知你。

我们不会泄露你的信息,也不会发送无关内容。随时可以退订。

Explore More Experts

Discover the researchers shaping the future of cancer treatment