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Translational Medicine / 转化医学Cancer Antisense Oligonucleotides
Adrian Krainer
PhD
🏢Cold Spring Harbor Laboratory🌐USA
St. Giles Foundation Professor
100
h-index
0
Key Papers
0
Key Contributions
👥Biography 个人简介
Adrian Krainer discovered the mechanism of splice-switching antisense oligonucleotides and developed nusinersen (Spinraza) for spinal muscular atrophy, the first approved splice-modulating ASO. His laboratory extends splice correction to cancer applications. He is a foundational figure in RNA splicing and ASO therapeutics.
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🧪Research Fields 研究领域
RNA splicing
splice-switching ASO
SMA nusinersen
cancer splicing correction
SR proteins
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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