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Translational Medicine / 转化医学Gastric Cancer, Targeted and Anti-Angiogenic Therapy

Kohei Shitara

MD

🏢National Cancer Center Hospital East🌐Japan

Chief of Department of Gastrointestinal Oncology

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👥Biography 个人简介

Kohei Shitara at National Cancer Center Hospital East is among the most prolific researchers in gastric cancer globally, having led or contributed to RAINBOW, DESTINY-Gastric, KEYNOTE-811, and numerous other landmark gastric cancer trials. His work on ramucirumab as second-line standard of care and his contributions to understanding T-DXd activity in HER2-positive gastric cancer have transformed the therapeutic landscape. He has been instrumental in conducting pivotal studies on nivolumab in Japan and globally in gastric and GEJ cancer. His research on molecular classification of gastric cancer and biomarker-guided therapy represents a major contribution to the field.

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🧪Research Fields 研究领域

ramucirumab gastric cancer
RAINBOW trial gastric
trastuzumab HER2 gastric
DESTINY-Gastric trastuzumab deruxtecan
nivolumab gastric Japan

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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